Piperazine and homopiperazine compounds
US4492696A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Feb 15, 1983 |
| Grant date | Jan 8, 1985 |
| Priority date | — |
| Expiry date | Feb 15, 2003 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D409/12
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Piperazine and homopiperazine compounds of the formula: ##STR1## in which: A is a hydrocarbon radical from C.sub.3 to C.sub.5, in a straight or branched chain, which may contain one or two double bonds, and optionally substituted by one or more OH; PA0 B is CH or a nitrogen atom; PA0 m is 2 or 3; PA0 X--Y-- represents --CH.dbd.CH-- (CR'R").sub.n -- in which n is zero or 1, and R' and R" are hydrogen or methyl; PA0 Z is oxygen or sulfur, PA0 R is hydrogen, alkyl from C.sub.1 to C.sub.5, cycloalkyl from C.sub.3 to C.sub.7, or phenyl optionally substituted by fluorine, chlorine or alkyl from C.sub.1 to C.sub.5, and PA0 T is hydrogen, fluorine, chlorine or alkyl from C.sub.1 to C.sub.5. These compounds and physiologically tolerable acid addition salts thereof may be used as medicines especially in the treatment of all kinds of tissular hypoxy.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.