Diphenylbutyl-1-acylpiperazines

US4492698A · kind A · utility

Inventors

• Anders Bjork · Bjärred, SE
• Aina L. Abramo · Bjärred, SE
• Erik G. Christensson · Lund, SE

Key dates

• Filing date: Jan 25, 1982
• Grant date: Jan 8, 1985
• Expiry date: Jan 25, 2002

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D295/192
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Novel compounds of the formula ##STR1## wherein R' is selected from the group consisting of alkyl straight or branch chained having from 2 to 10 carbon atoms, cycloalkyl having from 3 to 8 carbon atoms, aralkyl having from 7 to 9 carbon atoms, phenyl and substituted phenyl wherein the substituents of the substituted phenyl are selected from the group consisting of one to three F, Cl, Br, lower alkyl having from 1 to 5 carbon atoms, lower alkoxy having from 1 to 5 carbon atoms, alkylenedioxy having from 1 to 3 carbon atoms, --CF.sub.3 and --CN and pharmaceutically acceptable salts thereof which have been found to have utility for therapeutic treatment of mental disorders by reducing anti-aggressive behavior and a process for making the compounds.