Patent · US Expired

Indole and indoline carboxylic acid compounds and method of use

US4493843A · kind A · utility

2Cited by
7References
34Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 21, 1982
Grant dateJan 15, 1985
Priority date
Expiry dateMay 21, 2002

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D209/30
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Indole and indoline derivatives of the formula: ##STR1## wherein indicates a double bond or a single bond between carbon atoms, R.sup.1 represents hydrogen, alkyl of 1 through 6 carbon atoms, or alkyl of 1 through 6 carbon atoms substituted by one or more than one of the same type of substituents selected from the hydroxy group, alkenyl groups of 2 through 5 carbon atoms, and alkanoyloxy groups of 2 through 7 carbon atoms, and one of the symbols R.sup.2 represents alkyl of 6 through 24 carbon atoms and the other symbol R.sup.2 represents alkyl of 1 through 24 carbon atoms or hydrogen, and R.sup.3 represents alkyl of 1 through 6 carbon atoms or hydrogen, are new compounds possessing useful pharmacological properties. They are of use in the treatment of diabetes mellitus, hyperlipoproteinaemic states, of atherosclerosis, and of associated conditions.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.