Antiinflammatory 5H-tetrazolo (5,1-c)(1,4)benzodiazepine derivatives

US4495101A · kind A · utility

Assignee

• Amerimas Home Products, Inc. · US

Inventors

• Dieter Klaubert · Arroyo Grande, US
• Stanley C. Bell · Narberth, US
• Thomas W. Pattison · King of Prussia, US
• Richard Rees · Berlin, DE

Key dates

• Filing date: Apr 28, 1983
• Grant date: Jan 22, 1985
• Expiry date: Apr 28, 2003

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D487/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The compounds of the formula ##STR1## in which R is hydrogen, halogen, alkyl, alkoxy, hydroxyl, nitro or cyano; and PA0 R.sup.2 is .dbd.O, .dbd.S, H.sub.2, --SCH.sub.3, or an amino group; with the proviso that when R is chloro in 8-position, R.sup.2 must be other than oxygen or sulfur; or a pharmaceutically acceptable salt thereof.