Pharmaceutical compositions and methods for producing alpha antagonism
US4496558A · kind A · utility
12Cited by
9References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 26, 1983 |
| Grant date | Jan 29, 1985 |
| Priority date | — |
| Expiry date | Jan 26, 2003 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D223/16
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Pharmaceutical compositions and methods for producing alpha.sub.2 antagonism utilize, as active ingredients, 6-halo-N-substituted 2,3,4,5-tetrahydro-1H-3-benzazepines. These compositions are particularly useful for lowering intraocular pressure and for the treatment of abnormal cardiovascular conditions such as, for example, congestive heart failure, angina pectoris and thrombosis. The compositions and compounds of this invention, also, produce a reduction in blood pressure in hypertensive subjects and are, therefore, useful as antihypertensive agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.