Patent · US Expired

Derivatives of 3-aminopropane-1,2-diol

US4497813A · kind A · utility

17Cited by
3References
36Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 14, 1982
Grant dateFeb 5, 1985
Priority date
Expiry dateMay 14, 2002

Classification

  • Technology area (CPC B)Performing Operations; Transporting
  • CPC primaryB65D2571/00018
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Derivatives of 3-aminopropane-1,2-diol of the formula ##STR1## in which Ar represents optionally substituted aryl, PA1 n represents the number 0 or 1, and PA1 alk represents alkylene having 2 to 5 carbon atoms, the nitrogen atom and the oxygen atom, or, if n is zero, the phenyl radical, being separated from one another by at least two carbon atoms, and PA1 R.sub.1 and R.sub.2, independently of one another, each represents hydrogen or lower alkyl, or together they represent lower alkylene, oxa-lower alkylene, thia-lower alkylene, aza-lower alkylene or N-lower alkyl-aza-lower alkylene, and salts of such compounds, processes for their manufacture, medicaments containing the new compounds and their use for the treatment of Angina pectoris and cardiac arrhythmia, and as blood pressure-reducing agents, as well as for the treatment of reactive or endogenic states of depression.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.