2-Alkylthio-1-aminoalkyl-2-pyrroline-3-carbonitriles, compositions and use

US4499089A · kind A · utility

Assignee

• WARNER-LAMBERT COMPANY LLC · US

Inventors

• Hubert Barth · Emmendingen, DE
• Johannes Hartenstein · Kirchzarten, DE
• Gerhard Satzinger · Denzlingen, DE
• Edgar Fritschi · Giengen an der Brenz, DE
• Volker Ganser · Glückstadt, DE
• Horst-Dietmar Tauschel · Ettenheim, DE
• Gunter Wolf · Glückstadt, DE

Key dates

• Filing date: May 10, 1984
• Grant date: Feb 12, 1985
• Expiry date: May 10, 2004

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D207/38
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

2-Alkylthio-1-aminoalkyl-2-pyrroline-3-carbonitriles and pharmaceutically acceptable acid addition salts, processes for their preparation and formulation into pharmaceutical compositions as well as their activity as thrombocyte aggregation-inhibitors are described. The compounds are thus useful for the prophylaxis and therapy of thrombotic states.