Process for preparation of substituted formamidine and substituted N-iminomethyl piperidine
US4499274A · kind A · utility
5Cited by
4References
16Claims
0Family size
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Key dates
| Filing date | Mar 17, 1983 |
| Grant date | Feb 12, 1985 |
| Priority date | — |
| Expiry date | Mar 17, 2003 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D211/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
An improved process for preparing fenoctimine, which is 4-(diphenylmethyl)-1-[(octylimino)methyl]piperidine by: (1) reacting dimethylformamide with dimethyl sulfate to form a complex; (2) reacting the resultant dimethylformamide/dimethyl sulfate complex with n-octylamine and optionally with dimethylamine; (3) thereafter treating the reaction with aqueous base to form N,N-dimethyl-N'-octyl-formamidine; and (4) reacting said formamidine, without need for further purification, with 4-(diphenylmethyl) piperidine to obtain 4-(diphenylmethyl)-1-[(octylimino)-methyl]piperidine.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.