Reduction of trichloromethylpyridines to dichloromethylpyridines
US4499276A · kind A · utility
3Cited by
5References
7Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 14, 1983 |
| Grant date | Feb 12, 1985 |
| Priority date | — |
| Expiry date | Mar 14, 2003 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D213/61
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
2(6)-(Trichloromethyl)pyridines are reduced to the corresponding 2(6)-(dichloromethyl)pyridines by treatment with a strong base and an anionic reductant derived from a reductant source material selected from the group consisting of chloroform, dimethylsulfoxide, dimethylsulfone, and a ketone having a base-abstractable hydrogen, said treatment taking place in the presence of a polar, non-hydroxylic solvent and/or a phase transfer catalyst.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.