Patent · US Expired

Blood oxygenating and cerebral vasoregulating 20,21-dinoreburnamenines

US4501740A · kind A · utility

4Cited by
6References
21Claims
0Family size

Assignee

Inventors

Key dates

Filing dateSep 21, 1982
Grant dateFeb 26, 1985
Priority date
Expiry dateSep 21, 2002

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P9/00
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Novel 20,21-dinoreburnamenines of the formula ##STR1## wherein R is selected from the group consisting of hydrogen, alkyl of 1 to 4 carbon atoms and .dbd.CH.sub.2, the wavy line connecting to the E ring being a single bond when R is hydrogen or alkyl of 1 to 4 carbon atoms or a double bond when R is .dbd.CH.sub.2 and the dotted line being possibly an endo carbon-carbon bond when R is hydrogen or alkyl of 1 to 4 carbon atoms and their non-toxic, pharmaceutically acceptable acid addition salts in all their possible isomers forms, racemic mixtures and optical isomers having oxygenating and cerebral vasoregulating activity of great value and a novel process and intermediates for their preparation.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.