Thiazole compounds, a process for preparing same and a pharmaceutical composition containing the thiazole compounds
US4501750A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Sep 13, 1982 |
| Grant date | Feb 26, 1985 |
| Priority date | — |
| Expiry date | Sep 13, 2002 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D277/54
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention provides new thiazole compounds possessing immuno-modulating activity, i.e. thiazole compounds of the general formula (1): ##STR1## wherein R.sub.1 stands for a hydrogen or halogen atom or a lower alkyl, lower alkoxy, substituted or unsubstituted phenoxy, nitro or cyano group, R.sub.2 for a hydrogen atom or a lower alkyl or lower alkylthio group, and R for an .alpha.-halogenoalkyl group or the grouping: ##STR2## a process for preparing same and pharmaceutical compositions containing the thiazole compounds. More particularly, the present invention provides new thiazole compounds of the above general formula (1) which have immuno-modulating activity and are thus effective against immunodiseases such as chronic rheumatoid arthritis and also useful against viral diseases or for the immunotherapy of cancers, but show weak toxicity and are thus extremely desirous as medicines, a process for the preparation of the thiazole compounds and pharmaceutical compositions containing the thiazole compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.