Process for the preparation of E-isomers of 1-cyclohexyl-2-(1,2,4-triazol-1-yl)-1-penten-3-one derivatives

US4501897A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Wolf Reiser · Wuppertal, DE
• Hans-Ludwig Elbe · Wuppertal, DE
• Peter Feyen · Mettmann, DE

Key dates

• Filing date: Aug 16, 1983
• Grant date: Feb 26, 1985
• Expiry date: Aug 16, 2003

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D249/08
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

A process for the preparation of E-isomers of 1-cyclohexyl-2-(1,2,4-triazol-1-yl)-1-penten-3-one derivatives of the formula ##STR1## in which X and Y independently of one another represent hydrogen or halogen by contacting isomers of 1-cyclohexyl-2-(1,2,4-triazol-1-yl)-1-penten-3-one derivatives of the formula ##STR2## in which X and Y have the previously indicated meaning with at least one secondary amine, if desired in the presence of water and/or in the presence of a water immiscible solvent.