Extracellular nonmitogenic angiogenesis factor and method of isolation thereof from wound fluid
US4503038A · kind A · utility
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6Claims
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Key dates
| Filing date | Feb 25, 1983 |
| Grant date | Mar 5, 1985 |
| Priority date | — |
| Expiry date | Feb 25, 2003 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A nonmitogenic angiogenesis factor is isolated from wound fluid by dialysis to include materials in the molecular size range of 2,000 to 14,000, lyophilization, and chromatography. The nonmitogenic angiogenesis factor is identified by activity by corneal implant assay and by cell migration assay. The angiogenesis factor is also characterized by inactivity by mitogenesis assay.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.