Coagulant plasma-protein solution

US4503039A · kind A · utility

Assignee

• Biotest-Serum-Institut GmbH

Inventors

• Ronald Kotitschke · Dreieich, DE
• Wolfgang Stephan · Heidelberg, DE

Key dates

• Filing date: Dec 14, 1983
• Grant date: Mar 5, 1985
• Expiry date: Dec 14, 2003

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K38/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A coagulant plasma-protein solution obtained by adsorbing stabilized human plasma at least once with 20-40 mg of colloidal silicic acid per gram of plasma protein and separating the adsorbent from the adsorbate, a method of manufacturing the solution, and a pharmaceutical preparation containing the solution and intended for the intravenous treatment of complex disorders of the hemostatic system. The solution is low in fibrinogen and factors XI and XII but otherwise close in composition to the starting material.