[5(or 4)-(Pyridinyl)-2-pyrimidinyl]ureas and cardiotonic use thereof
US4504482A · kind A · utility
9Cited by
1References
8Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 28, 1983 |
| Grant date | Mar 12, 1985 |
| Priority date | — |
| Expiry date | Jul 28, 2003 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D401/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
N-R-N'-R'-N-[4(or 5)-PY-2-pyrimidinyl]ureas (I) or salts thereof, where PY is 4- or 3-pyridinyl or 4- or 3-pyridinyl having one or two lower-alkyl substituents, R' is hydrogen or methyl and R is methyl or ethyl when PY is attached to the 4-position of the pyrimidine ring or R is hydrogen, ethyl or n-butyl when PY is attached to the 5-position of the pyrimidine ring are useful as cardiotonic agents. The preparations of I and their cardiotonic use are shown.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.