Preparation of anthralin solutions or suspensions in aromatic esters and their use for diseases of the skin and nails
US4504494A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jan 20, 1983 |
| Grant date | Mar 12, 1985 |
| Priority date | — |
| Expiry date | Jan 20, 2003 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61Q5/02
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An oxidation-stable composition is useful for the treatment of diseases of the skin and nails, which comprises a solution of dispersion of anthralin in an aromatic ester of the formula: ##STR1## wherein R represents H, OH, CH.sub.3, or OCH.sub.3, PA0 n is 1 or 2; PA0 R.sub.1 represents a linear or branched alkyl radical having 1 to 18 carbon atoms; a cycloalkyl radical having 4 to 6 carbon atoms which is optionally substituted by an alkyl radical having 1 to 3 carbon atoms; an arylalkyl or arylalkenyl radical in which the alkyl or alkenyl radical has 1 to 3 carbon atoms; or a phenyl radical optionally substituted by an alkyl radical having 1 to 3 carbon atoms or by an alkoxy radical having 1 or 2 carbon atoms; PA0 X represents the divalent radical --CH.sub.2 --, --CH.sub.2 --CH.sub.2 --, or --CH.dbd.C--; and t is 0 or 1.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.