Method for producing L-histidine by fermentation
US4504581A · kind A · utility
5Cited by
2References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 10, 1982 |
| Grant date | Mar 12, 1985 |
| Priority date | — |
| Expiry date | Dec 10, 2002 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/839
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
L-Histidine producing microorganisms which have been constructed by introducing a recombinant plasmid DNA inserted on a chromosomal DNA fragment into a recipient strain of the genus Bacillus. These microorganisms are employed to produce L-histidine in higher than normal yields. The recombinant plasmid DNA inserted is obtained from a donor mutant strain of Bacillus subtilis which is resistant to certain L-histidine antagonists. The resistant plasmid confers the properties of the mutant strain upon the recipient Bacillus subtilis to make its high yield of product even higher.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.