Patent · US Expired

Epimerization of malonic acid esters

US4504658A · kind A · utility

51Cited by
6References
7Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 14, 1983
Grant dateMar 12, 1985
Priority date
Expiry dateJun 14, 2003

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY02P20/55
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

A compound represented by the formula (II) epimerizes by the action of a base and the product is precipitated for shifting the equilibrium to yield the corresponding epimer represented by the formula (I). ##STR1## wherein Ar is an optionally substituted aryl or heterocyclic group; PA1 Tet is an optionally substituted tetrazolyl group and PA1 B.sup.1 and B.sup.2 are each ester forming group in the field of penicillin or cephalosporin chemistry.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.