N-Pyrazolylalkylenediamine intermediates

US4507488A · kind A · utility

Assignee

• Boehringer Mannheim GmbH · DE

Inventors

• Fritz Wiedemann · Weinheim, DE
• Ewald Rieger · Frankenthal (Pfalz), DE

Key dates

• Filing date: Apr 11, 1983
• Grant date: Mar 26, 1985
• Expiry date: Apr 11, 2003

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D487/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

New N-heteroarylalkylenediamine ##STR1## wherein R.sub.1 and R.sub.2 each independently is hydrogen, an alkyl radical containing up to 6 carbon atoms, or a benzyl radical, PA0 X is an alkylene radical containing 2 to 6 carbon atoms, PA0 A is a mono- or bicyclic heteroaromatic radical, which can be partly hydrogenated, with the proviso that it contains 2 or 3 adjacent ring heteroatoms, whereby the bound ring heteroatoms can be an oxygen atom and a nitrogen atom or 2 or 3 nitrogen atoms, and PA0 R.sub.3, R.sub.4, R.sub.5, R.sub.6 and R.sub.7 each independently is hydrogen, or an alkyl radical containing up to 6 carbon atoms, which can be substituted by hydroxyl, carbamyl, nitrile or carboxyl, an alkenyl radical containing 2 to 6 carbon atoms, a phenyl or carbamyl radical or one of the divalent substituents oxygen or sulphur, or a salt thereof. The compounds are intermediates in the synthesis of cardioactive compounds.