Patent · US Expired

2-Hydroxymethyl-quinoxaline-1,4-dioxide derivatives, a process for preparing same and compositions containing same

US4511717A · kind A · utility

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5References
4Claims
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Assignee

Inventors

Key dates

Filing dateMar 27, 1984
Grant dateApr 16, 1985
Priority date
Expiry dateMar 27, 2004

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P31/00
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The invention relates to new 2-hydroxymethyl-quinoxaline-1,4-dioxide derivatives of the general formula (I) ##STR1## wherein A represents an amino group, or a group of the general formula --NH--COOR.sub.1, wherein R.sub.1 stands for a C.sub.2-4 alkyl group, or a group of the general formula --NH--CX--NH.sub.2, wherein PA1 X denotes an oxygen or sulfur atom, or a group of the formula --NH--C(NH)--NH.sub.2, or a group of the general formula --NH--R.sub.2, wherein R.sub.2 represents a C.sub.1-6 alkyl, a phenyl, a benzyl, a hydroxyl or a hydroxy-(C.sub.2-4 alkyl) group, or a group of the general formula --NH--CO--R.sub.3, wherein R.sub.3 stands for a C.sub.1-20 alkyl group or a phenyl group optionally substituted by one, two or three identical or different substituent(s) selected from the group consisting of nitro, hydroxyl, amino, C.sub.1-3 alkoxy and halogen; a naphtyl group optionally substituted by a hydroxyl group, a phenyl-(C.sub.1-3 alkyl) group, a pyridyl, a piperidyl, a pyrazinyl, a pyrimidyl, a 1,2,4-triazinyl, a furyl, a nitrofuryl or an .alpha.,.alpha.-diphenyl-.alpha.-hydroxymethyl group. Due to their antimicrobial and weight-gain increasing effects, the new compounds of t…

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