Patent · US Expired

Oral product for controlling gingivitis

US4514382A · kind A · utility

21Cited by
10References
11Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJan 16, 1984
Grant dateApr 30, 1985
Priority date
Expiry dateJan 16, 2004

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K8/4946
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

An oral composition for treating gingivitis and periodontitis comprising an oral vehicle and an effective amount of the water insoluble antigingivitis agent, imidazolyl-1-1-(p-chlorophenoxy) 3-3-dimethyl 2-butanone solubilized in a nonionic compound containing a mixture of hydrophobic and hydrophilic groups of sufficient length to effect solubilization in an aqueous vehicle, in the weight ratio of 1:1 to 25:1 and preferably 3:1 to 25:1 solubilizer:imidazoyl compound, said agent being selectively effective against the gram negative anaerobic micro-organisms associated with periodontitis.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.