Oral product for controlling gingivitis
US4514382A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jan 16, 1984 |
| Grant date | Apr 30, 1985 |
| Priority date | — |
| Expiry date | Jan 16, 2004 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K8/4946
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An oral composition for treating gingivitis and periodontitis comprising an oral vehicle and an effective amount of the water insoluble antigingivitis agent, imidazolyl-1-1-(p-chlorophenoxy) 3-3-dimethyl 2-butanone solubilized in a nonionic compound containing a mixture of hydrophobic and hydrophilic groups of sufficient length to effect solubilization in an aqueous vehicle, in the weight ratio of 1:1 to 25:1 and preferably 3:1 to 25:1 solubilizer:imidazoyl compound, said agent being selectively effective against the gram negative anaerobic micro-organisms associated with periodontitis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.