Fluorinated erythromycin compounds and a process for preparation
US4514562A · kind A · utility
14Cited by
2References
24Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Nov 22, 1982 |
| Grant date | Apr 30, 1985 |
| Priority date | — |
| Expiry date | Nov 22, 2002 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P31/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Fluorinated derivatives of erythromycins A, B, C and D, having antibiotic activity, are prepared, starting from 8,9-anhydroerythromycin 6,9-hemiacetals or their N-oxides, through the reaction with a compound capable of generating electrophilic reactive fluorine, the resulting reaction product undergoing thereafter a reduction, possibly together with a methylation, to the corresponding (8S)-8-fluoroerythomycins.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.