Collagen-thrombin compositions
US4515637A · kind A · utility
148Cited by
5References
10Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Nov 16, 1983 |
| Grant date | May 7, 1985 |
| Priority date | — |
| Expiry date | Nov 16, 2003 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L2400/04
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A method of forming a collagen-thrombin hemostatic composition is comprised of forming a homogeneous aqueous admixture of collagen and thrombin at a basic pH and lyophilizing the collagen-thrombin admixture to form a stable collagen sponge having thrombin therein. The collagen utilized in the process is absorbable when placed in vivo. Additionally, a lyophilized collagen product is comprised of collagen which is absorbable when placed in vivo and thrombin distributed within the collagen. The collagen product is storage stable.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.