2'-Substituted-spiro[benzofuran-2(3H),1'-cycloalkanes] and their analgesic and anti-depressant compositions
US4517311A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Sep 13, 1982 |
| Grant date | May 14, 1985 |
| Priority date | — |
| Expiry date | Sep 13, 2002 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C255/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
2'-Substituted-spiro[benzofuran-2(3H),1'-cycloalkanes] and methods of praparing same are described. On the aromatic portion of the benzofuran ring, there may be a substituent or substituents including halogen, amino, lower-alkyl-substituted amino, lower alkyl, lower alkoxy, hydroxy and nitro. The substituents at the 2-position of the cycloalkane ring are --(CH.sub.2).sub.n NR.sup.1 R.sup.2 where n is 0, 1 or 2 and R.sup.1 and R.sup.2 are each independently hydrogen and alkyl of 1-3 carbons. These compounds are useful as antidepressants and analgesics. Various other compounds which are useful as intermediates for preparing the aforementioned compounds and methods for preparing same are also described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.