Patent · US Expired

Naphthalene and 2-oxo-benzopyran acids and derivatives and pharamaceutical use thereof

US4518612A · kind A · utility

2Cited by
1References
11Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 21, 1983
Grant dateMay 21, 1985
Priority date
Expiry dateDec 21, 2003

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D311/16
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

There are described compounds of formula I, ##STR1## in which Ra, Rb, Rc, Rd, Re, Rf and Rg, which may be the same or different, each represent hydrogen, amino, hydroxy, alkoxy, alkenyloxy, halogen, acyl, alkenyl, alkyl, or alkoxy substituted by phenyl, PA0 Rh is hydrogen, alkyl or --COOH. PA0 X is a hydrocarbon chain containing from 2 to 10 carbon atoms and optionally substituted by a hydroxy group, PA0 A has no significance or represents Y, OY, or SY and Y represents a C 1 to 4 hydrocarbon chain which is optionally substituted by alkyl C 1 to 4, PA0 E and G, which may be the same or different, each represent --O--, --S-- or --CH.sub.2 --, provided that at least one of E and G is --O-- or --S--, PA0 L, together with the carbon atoms to which it is attached, forms a benzene, furan, thiophene, pyrrole, or pyran-2-one ring, and pharmaceutically acceptable derivatives thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.