Process for producing sulfonylureas
US4518776A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 8, 1983 |
| Grant date | May 21, 1985 |
| Priority date | — |
| Expiry date | Jul 8, 2003 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D333/38
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
There is described a process for producing sulfonylureas of the formula ##STR1## wherein G is an unsubstituted or substituted furanyl, thienyl, pyrrolyl, pyridinyl or phenyl radical, PA0 X is alkyl, haloalkyl, alkoxy, alkylthio, halogen, haloalkoxy, alkylamino or dialkylamino, PA0 Y is alkyl, alkoxy or haloalkoxy, PA0 Z is a nitrogen atom or the methyne group --CH.dbd.. This novel process comprises reacting a sulfonamide of the formula EQU G--SO.sub.2 --NH.sub.2, in the presence of a base, with a chloroformic acid ester of the formula EQU Cl--CO--Q--T, or a sulfonyl chloride of the formula EQU G--SO.sub.2 Cl, in the presence of a base, with a urethane of the formula EQU H.sub.2 N--CO--Q--T; and converting the formed carbamate of the formula EQU G--SO.sub.2 --NH--CO--Q--T by reaction with an amine of the formula ##STR2## into the sulfonylurea of the above formula. There is also described novel sulfonylcarbamates of the above formula as intermediates.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.