Cephem compounds
US4521413A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Sep 2, 1982 |
| Grant date | Jun 4, 1985 |
| Priority date | — |
| Expiry date | Sep 2, 2002 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/55
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention relates to cephem compounds of high antimicrobial activity, of the formula: ##STR1## wherein R.sup.1 is amino or a protected amino group; PA0 R.sup.2 is lower alkyl which may be substituted with one carboxy, lower alkenyl, lower alkynyl, cyclo (lower) alkyl or cyclo (lower) alkenyl; PA0 R.sup.3 is lower alkylamino, N-(lower) alkanoyl (lower) alkylamino, di (lower) alkylamino, sulfo (lower) alkylamino, hydroxy (lower) alkylamino, N-(lower) alkanoylhydroxy (lower) alkylamino, alkanoyloxy (lower) alkyl, alkenoyloxy (lower) alkyl, lower alkoxy (lower) alkoxy (lower) alkyl, di (lower) alkylamino (lower) alkyl, lower alkylthio (lower) alkyl, lower alkylthio, lower alkoxy, lower alkoxy (lower) alkoxy, hydroxy (lower) alkoxy, lower alkanesulfonyl (lower) alkyl, hydroxy (lower) alkylthio, di (lower) alkylamino (lower) alkylthio, tetrazolyl, tetrazolylthio, tetrazolylthio (lower) alkyl or dihydrotriazinylthio (lower) alkyl substituted with oxo, hydroxy and lower alkyl; and PA0 R.sup.4 is hydrogen or lower alkyl; and pharmaceutically acceptable salts thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.