Particle reagent size distribution measurements for immunoassay
US4521521A · kind A · utility
28Cited by
8References
11Claims
0Family size
Assignee
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Key dates
| Filing date | Mar 11, 1983 |
| Grant date | Jun 4, 1985 |
| Priority date | — |
| Expiry date | Mar 11, 2003 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S436/817
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A highly sensitive and rapid method for quantitatively assaying analytes in liquid media by directly measuring changes in particle size distribution of reagent particles having analyte insolubilized thereon in a system undergoing antibody-induced aggregation has been developed. The amount of analyte initially present can be determined by measuring the change in the distribution of particle size with time, the concentration of a particular size particle at a given time, the rate of formation of a particular size particle, or the steady-state maximum concentration for a particular size particle.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.