Indole derivatives of tryptamine and cardiovascular compositions thereof
US4522824A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Mar 21, 1983 |
| Grant date | Jun 11, 1985 |
| Priority date | — |
| Expiry date | Mar 21, 2003 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D209/42
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to derivatives of tryptamine of formula: ##STR1## in which: R.sub.1 represents a CH.sub.2 OH group, a --C.tbd.N group, ##STR2## or a --COOR.sub.6 group in which R.sub.4, R.sub.5 and R.sub.6 denote a lower alkyl group or hydrogen; PA1 R.sub.2 represents hydrogen or a C.tbd.N group; PA1 R.sub.3 denotes hydrogen, a CH.sub.3 group or a CH.sub.2 OH group, and the addition salts of the products of formula I with the pharmaceutically acceptable, mineral or organic acids. It also relates to a process for preparing said compounds and to the drugs active on the cardiovascular system, containing said compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.