Certain 1,3-oxazolo[4,5H]quinolines useful as anti-allergy agents
US4522947A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Mar 18, 1983 |
| Grant date | Jun 11, 1985 |
| Priority date | — |
| Expiry date | Mar 18, 2003 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D215/28
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
New quinoline compound, and the corresponding 1,2-; 1,3-; and 1,4-benzodiazines, the quinoline compounds being of the formula: ##STR1## and salts thereof, wherein R.sub.1 and R.sub.2 are independently hydrogen, lower alkyl, halo, trifluoromethyl, amino, lower alkyl amino, lower acylamino, cyano, aryl, aryl/lower alkylene, nitro, lower alkynyl, lower alkenyl, lower alkyl sulfinyl, lower alkyl sulfonyl, lower alkoxycarbonyl, carboxyl, lower alkoxy, lower alkanoyl, or lower alkenoyl, PA1 Y is oxygen, sulfur, nitrogen or R.sub.3 N wherein R.sub.3 is hydrogen, lower alkyl, alkenyl, alkynyl, aryl, aralkyl, acyl, aminoalkyl, or carboxyalkyl, PA1 Z is oxygen, sulfur or nitrogen, PA1 X is cyano, carbalkoxyl, carboxyl, formyloximino, tetrazolyl, carbalkoxyalkyl or carboxyalkyl, and PA1 m is 0 or 1, are useful as medicinals, especially for treatment of asthma, and/or as intermediates in the preparation of compounds useful for treating asthma.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.