Process for the preparation of 1,1'-diacetals

US4524202A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Lutz F. Tietze · Göttingen, DE
• Roland Fischer · Bochum, DE

Key dates

• Filing date: Jun 24, 1982
• Grant date: Jun 18, 1985
• Expiry date: Jun 24, 2002

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07H17/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention relates to a process for the synthesis of 1,1'-diacetals, which method is also suitable for the stereoselective synthesis of glycosides with the 1,1'-diacetal structure. The process involves reacting a silyl compound of formula (II) with an acetal of formula (III) in the presence of a catalyst of formula (IV) or (V) in a suitable solvent.