Process for the preparation of the anhydride of N-formyl-L-aspartic acid
US4526985A · kind A · utility
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Key dates
| Filing date | Jul 18, 1983 |
| Grant date | Jul 2, 1985 |
| Priority date | — |
| Expiry date | Jul 18, 2003 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D307/66
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process for the preparation of the anhydride of N-formyl-L-aspartic acid by reacting L-aspartic acid with nearly stoichiometric amounts of formic acid and acetic anhydride, under controlled conditions of temperature, reaction and addition times. The product is a known intermediate in the synthesis of .alpha.-L-aspartyl-L-phenylalanine methyl ester, a known sweetening agent.
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