Benzoyl-phenyl-piperidine derivatives
US4528294A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jun 24, 1982 |
| Grant date | Jul 9, 1985 |
| Priority date | — |
| Expiry date | Jun 24, 2002 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D211/46
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to new benzoyl-phenyl-piperidine derivatives selected from the group consisting of: PA0 (i) 2-piperidinobenzophenones of the general formula: ##STR1## in which: R.sub.1, R.sub.2 and R.sub.3, which are identical or different, each represent an atom of hydrogen, a hydroxy group, CF.sub.3, a halogen, a lower alkyl group or a lower alkoxy group; PA1 R.sub.4 represents an atom of hydrogen, a halogen, an NO.sub.2 group, an NR'R" group [where R' and R", which are identical or different, represent an atom of hydrogen, a lower alkyl group or a CO.sub.2 R group (where R represents a lower alkyl group or a benzyl group)]; PA1 R.sub.5 and R.sub.6, which are identical or different, each represent an atom of hydrogen, a C.sub.1 -C.sub.4 -alkyl group, an OH group, a phenyl group or a benzyl group; and PA0 (ii) acid addition salts thereof. The invention also relates to the method for preparing these new derivatives and to their use in therapeutics, particularly as immunostimulant and immunoadjuvant agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.