Preparation of substituted thiadiazolyloxyacetamides

US4528379A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Reimer Colln · Wuppertal, DE
• Karl H. Mohrmann · Bensberg, DE

Key dates

• Filing date: Jul 18, 1983
• Grant date: Jul 9, 1985
• Expiry date: Jul 18, 2003

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D285/13
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

In a process for the preparation of a substituted thiadiazolyloxyacetamide of the formula ##STR1## in which R.sup.1 and R.sup.2 each independently is hydrogen, alkyl, alkenyl, alkenyl, alkinyl, optionally substituted cycloalkyl or cycloalkenyl, halogenoalkyl, alkoxyalkyl, alkoxy, aralkyl or optionally substituted aryl, or PA0 R.sup.1 and R.sup.2, together with the nitrogen atom to which they are bonded, form an optionally substituted heterocyclic structure which can contain further hetero atoms, PA0 One of X and Y is a nitrogen atom and the other a C-R.sup.3 a grouping, and PA0 R.sup.3 is alkyl, alkoxy, alkylthio, alkylsulphonyl, halogenoalkyl, aralkyl, aralkoxy, aralkythio or optionally substituted aryl, wherein a substituted 5-halogenothiadiazole of the formula ##STR2## in which Hal is halogen, is reacted with a hydroxyacetamide of the formula ##STR3## in the presence of a base as an acid acceptor and, optionally in the presence of a diluent, the improvement which comprises employing lithium hydroxide or its hydrate as the base, and carrying out the reaction at a temperature between about -10.degree. C. and +60.degree. C. The end products are known herbicides.