Substituted 1-azabicyclo(3.2.0)hept-6-en-2-one-7-carboxylic acids
US4529597A · kind A · utility
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Key dates
| Filing date | Apr 19, 1982 |
| Grant date | Jul 16, 1985 |
| Priority date | — |
| Expiry date | Apr 19, 2002 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D477/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Disclosed are substituted 1-azabicyclo [3.2.0]-hept-6-en-2-one-7-carboxylic acids (I) and their pharmaceutically acceptable salts and esters which are useful as antibiotics. ##STR1## wherein R is hydrogen, and, inter alia, unsubstituted and substituted alkyl, aryl, aralkyl; R.sup.8 is, inter alia, unsubstituted and substituted alkyl, alkenyl, aryl, and aralkyl. Also disclosed are processes for the preparation of such compounds; pharmaceutical compositions comprising such compounds; and methods of treatment comprising administering such compounds and compositions when an antibiotic effect is indicated.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.