2-Thiazolamine derivatives, process for preparing same, and pharmaceutical compositions comprising same

US4532137A · kind A · utility

Assignee

• Mitsui Toatsu Chemicals, Incorporated · JP

Inventors

• Isao Sakano · Yokohama, JP
• Tatsuro Yokoyama · Mobara, JP
• Seitaro Kajiya · Yokohama, JP
• Yutaka Okazaki · Mobara, JP
• Hiroshi Tokuda · Mobara, JP
• Hiroshi Kawazura · Chiba, JP
• Mikio Kumakura · Mobara, JP
• Takuo Nakano · Yokohama, JP
• Akira Awaya · Yokohama, JP

Key dates

• Filing date: Jan 6, 1984
• Grant date: Jul 30, 1985
• Expiry date: Jan 6, 2004

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P37/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Disclosed are 2-thiazol derivatives having the general formula ##STR1## where R.sub.1 and R.sub.2 independently represent lower alkyl radicals having 1 to 4 carbon atoms and X represents a lower alkyl radical, a lower alkoxy radical, a lower alkoxycarbonyl radical, a halogenoalkoxy radical, a radical of the formula ##STR2## or a radical of the formula ##STR3## Also disclosed are a process for preparing the derivatives and pharmaceutical compositions having immunomodulatory activity which comprise the derivatives as the active ingredient.