Theophylline immunogens, antibodies, labeled conjugates, and related derivatives
US4533493A · kind A · utility
5Cited by
4References
15Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 27, 1981 |
| Grant date | Aug 6, 1985 |
| Priority date | — |
| Expiry date | Aug 27, 2001 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/961
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Theophylline immunogens, antibodies prepared therefrom, labeled theophylline conjugates, synthetic intermediates, and the use of such antibodies and labeled conjugates in immunoassays for determining theophylline. The immunogens comprise theophylline coupled at its 9-position to an immunogenic carrier material. Likewise, the labeled conjugates and synthetic intermediates are 9-position derivatives of theophylline or synthetic precursors thereof. The antibody and labeled reagents are particularly useful in homogeneous nonradioisotopic immunoassays for measuring theophylline in biological fluids such as serum.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.