Patent · US Expired

Derivatives of 2-piperazino-pyrimidine, methods for their preparation and their utilization as drugs or intermediates for drugs

US4535080A · kind A · utility

10Cited by
6References
8Claims
0Family size

Assignee

Inventors

Key dates

Filing dateAug 24, 1983
Grant dateAug 13, 1985
Priority date
Expiry dateAug 24, 2003

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D239/60
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Compounds are disclosed as useful as drugs or as intermediates for the manufacture of drugs, the compounds having the formula: ##STR1## in which X is hydrogen, chlorine, alkyl, alkoxy or alkylthio having 1 to 3 carbon atoms, R.sub.2 is hydrogen or alkyl having 1 to 3 carbon atoms, Y.sub.2 is chlorine and Y.sub.1 is chlorine or ##STR2## in which R.sub.1 is hydrogen, straight or branched chain alkyl having 1 to 7 carbon atoms, cycloalkyl having 3 to 7 carbon atoms or cycloalkylalkyl having 4 to 8 carbon atoms, or Y.sub.2 and Y.sub.1 are both OH. Also disclosed are methods for preparation of the compounds.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.