N-substituted amino acid derivatives
US4535177A · kind A · utility
2Cited by
4References
16Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 14, 1983 |
| Grant date | Aug 13, 1985 |
| Priority date | — |
| Expiry date | Nov 14, 2003 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D209/20
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Optical isomeric compounds having the general formula ##STR1## are prepared by: reacting by catalytic hydrogenation a compound of the formula ##STR2## with a compound of the formula ##STR3## wherein R, R.sub.1, R.sub.2 and R.sub.3 are as defined herein, to form a mixture of isomers in a ratio of L(S)L(S)>D(R)L(S); and recovering the (S,S) diastereomer by selectively precipitating an acid salt of the (S,S) ester from the solution.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.