Process for the preparation of alpha-aryl-propionic acids and alkaline salts thereof
US4536595A · kind A · utility
13Cited by
6References
16Claims
0Family size
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Key dates
| Filing date | Sep 17, 1982 |
| Grant date | Aug 20, 1985 |
| Priority date | — |
| Expiry date | Sep 17, 2002 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C51/10
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Alpha-arylpropionic acids and alkaline salts thereof are prepared by catalytic reaction with carbon monoxide of the corresponding secondary halids in an anhydrous low alcohol solvent in the presence of a salt of cobalt hydrocarbonyl and in further presence of alkaline hydroxides under substantially ambient temperature and pressure conditions. The products obtained find useful applications in the field of pharmaceutics (analgesics, antipyretics, etc.) and as intermediates for chemical syntheses of fine chemicals, phytodrugs, etc.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.