Patent · US Expired

4-Demethoxy-3'-desamino-2'-halo-anthracycline and pharmaceutical composition containing same

US4537882A · kind A · utility

11Cited by
6References
12Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 10, 1984
Grant dateAug 27, 1985
Priority date
Expiry dateMay 10, 2004

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07H15/252
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Compounds of the formula (I), acid addition salts thereof, and pharmaceutical preparations containing the same are disclosed ##STR1## wherein R.sup.1 is hydroxy; one of X and X' is hydrogen and the other is a halogen atom selected from the group consisting of fluorine, chlorine, bromine, and iodine; one of Y and Y' is hydrogen and the other is selected from the group consisting of hydrogen, hydroxy and --OCOR; one of Z and Z' is hydrogen and the other is hydrogen, hydroxy or --OCOR; and R is a lower alkyl group.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.