Benzothiazepine derivatives and their method of preparation
US4539151A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jun 28, 1984 |
| Grant date | Sep 3, 1985 |
| Priority date | — |
| Expiry date | Jun 28, 2004 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/55
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
This invention relates to benzothiazepine derivatives of the general formula ##STR1## where Y is hydrogen, a CHR.sub.3 --COOR.sub.1 group, an alkanoyl group or a --COO(CH.sub.2).sub.n R.sub.4 group where R.sub.1 is hydrogen or a lower alkyl group, R.sub.3 is hydrogen, an alkyl group, an alkylphenyl group or an aryl-lower alkyl group, R.sub.4 is an aryl group and n is a whole number of 1 to 10, and to their method of preparation. The benzothiazepine derivatives of this invention, including their salts, have an inhibitory effect on the angiotensin converting enzyme and are useful as raw materials or intermediates for the synthesis of antihypertensive agents and as intermediates for the manufacture of other drugs, agricultural chemicals and industrial chemicals.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.