Sustained release pharmaceutical compositions
US4539199A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jun 1, 1982 |
| Grant date | Sep 3, 1985 |
| Priority date | — |
| Expiry date | Jun 1, 2002 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K47/58
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Pharmaceutical compositions for sustained release of pharmaceutical compounds comprising a reaction product of a water soluble salt of a pharmaceutically active compound containing a primary, secondary or tertiary amino group, and an alkali or ammonium salt of a synthetic copolymer containing an acid group, and selected from the group consisting of methacrylic acid/methacrylic acid methyl ester, methacrylic acid/acrylic acid methyl ester and methacrylic acid/acrylic acid methyl ester/methacrylic acid methyl ester copolymers and a pharmaceutically acceptable excipient. The water soluble salt of a pharmaceutically active compound containing a primary, secondary or tertiary amino group is reacted in aqueous medium with an alkali or ammonium salt of a copolymer selected from the group consisting of the above mentioned copolymers, and the resulting product is converted into a pharmaceutical composition.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.