Patent · US Expired

Tetrazole derivatives, anti-ulcer composition containing the same and method for treating ulcers

US4540703A · kind A · utility

7Cited by
2References
52Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 23, 1981
Grant dateSep 10, 1985
Priority date
Expiry dateDec 23, 2001

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P29/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Tetrazole derivatives of the formula: ##STR1## wherein R.sup.1 is an optional defined substituent; A is sulfur or a lower alkylene-thio; l is 0 or 1; B is a lower alkylene; R.sup.2 is hydroxy, a lower alkoxy, or a group: ##STR2## wherein R.sup.3 and R.sup.4 are optional defined substituents, or the R.sup.3 and R.sup.4 may combine together with the nitrogen atom to which they are joined to form a defined heterocyclic group, and a pharmaceutically acceptable salt thereof, which have prophylactic or therapeutic activities against peptic and/or duodenal ulcers and also anti-inflammatory activity and are useful as an anti-ulcer or anti-inflammatory drug; processes for the preparation of the tetrazole derivatives; and pharmaceutical composition containing said tetrazole derivatives.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.