Trinitroglycerol sustained release vehicles and preparation therefrom
US4542013A · kind A · utility
30Cited by
1References
8Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Aug 16, 1983 |
| Grant date | Sep 17, 1985 |
| Priority date | — |
| Expiry date | Aug 16, 2003 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/21
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A trinitroglycerol-containing substantially disaccharide-free polymeric diffusion matrix is provided for the transdermal systemic delivery of trinitroglycerol through the skin of a patient. The polymeric diffusion matrix contains sufficient trinitroglycerol to be released over a prolonged period of time and comprises a first lower molecular weight, partially hydrolyzed polyvinylalcohol component, a second higher molecular weight, essentially fully hydrolyzed polyvinylalcohol component, and glycerol.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.