Patent · US Expired

2-(1-Piperazinyl) pyrimidines, their salts and pharmaceutical compositions containing them

US4542136A · kind A · utility

6Cited by
1References
3Claims
0Family size

Assignee

Inventors

Key dates

Filing dateOct 28, 1983
Grant dateSep 17, 1985
Priority date
Expiry dateOct 28, 2003

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P25/18
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention relates to a process for preparing 2-(1-piperazinyl) pyrimidines of formula: ##STR1## in which one of the groups T and Q represents hydrogen, a hydroxyl or lower alkanoyloxy group, and the other represents hydrogen; and X represents: PA1 a group --CO--R.sub.1 PA1 a group ##STR2## an alkylene-COOY group an alkylene-CO--W group, according to which a 2-(1-piperazinyl) pyrimidine of formula: ##STR3## is reacted with a compound of formula AX in which A is selected from an atom of halogen and an activator group of the carboxylic function of the radical X.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.