Cycloaliphatic ketoamines

US4542159A · kind A · utility

Assignee

• Degussa Akteinsellschaft · DE

Inventors

• Jurgen Engel · Alzenau, DE
• Axel Kleemann · Hanau, DE
• Klaus Posselt
• Fritz Stroman · Offenbach, DE
• Klaus Thiemer · Hanau, DE

Key dates

• Filing date: May 15, 1979
• Grant date: Sep 17, 1985
• Expiry date: May 15, 1999

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C2603/74
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

There are prepared compounds of the formula: ##STR1## wherein X is the group >C.dbd.O or >CH(OH), Y is the group ##STR2## R.sub.2 is hydrogen or C.sub.1 to C.sub.6 alkyl, R.sub.3 is hydrogen or a hydroxy group and R.sub.1 is the adamantyl group or a saturated or single unsaturated C.sub.3 to C.sub.16 cycloalkyl group where the C.sub.3 to C.sub.16 cycloalkyl group can be substituted by a C.sub.1 -C.sub.4 alkyl group or a halogen atom and their salts. The compounds are useful in dilating the peripheral blood vessels and in lowering blood pressure.