Process for the separation of (S,S) diastereoisomers
US4542234A · kind A · utility
6Cited by
4References
4Claims
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Assignee
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Key dates
| Filing date | Oct 6, 1983 |
| Grant date | Sep 17, 1985 |
| Priority date | — |
| Expiry date | Oct 6, 2003 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C227/34
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The (S,S) optical isomer of a compound having the general formula ##STR1## wherein R and R.sub.1-5 are as defined herein, is recovered essentially free of the (R,S) and (S,R) isomers, by forming a solution of the esters of the (S,S) and the (R,S) and/or (S,R) isomers of said compound, selectively precipitating an acid salt (e.g. maleate) of the (S,S) ester from the solution, and treating the precipitate to form the desired free acid.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.