Basic heptapeptide vasopressin antagonists
US4543349A · kind A · utility
10Cited by
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23Claims
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Key dates
| Filing date | Aug 28, 1984 |
| Grant date | Sep 24, 1985 |
| Priority date | — |
| Expiry date | Aug 28, 2004 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S930/15
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Certain cyclic vasopressin-like peptides, which have an .omega.-amino- or guanidinoalkyl substituent attached to the cysteine in the 6-position of the ring, have vasopressin antagonist activity. A species of this series of new compounds is [1-(.beta.-mercapto-.beta.,.beta.-cyclopentamethylenepropionic acid)-2-(O-ethyl-D-tyrosine)-4-valine-8-(1,5-diaminopentane)-8-desarginine -9-desglycinamide]-vasopressin.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.