Antihypertensive substituted imidazole derivatives
US4544664A · kind A · utility
31Cited by
3References
12Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 7, 1982 |
| Grant date | Oct 1, 1985 |
| Priority date | — |
| Expiry date | Jul 7, 2002 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D405/06
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention provides novel compounds of the formula: ##STR1## wherein the various substituents are defined herein below. Processes for the preparation of these compounds are described, as are novel pharmaceutical compositions comprising at least one of the compounds of their salts. The compounds and their non-toxic salts exhibit valuable pharmacological activity and are useful in the treatment of mammals, especially as antihypertensive agents. Furthermore, some of the compounds have proved to possess antithrombotic and diuretic activity. Antimycotic and antifungal properties have also been found.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.